BDBM345794 N-(2-(2-ethyl-6-fluorophenoxy)-6- (1-methyl-6-oxo-1,6- dihydropyridin-3-yl)pyrimidin-4- yl)propane-1-sulfonamide::US10202360, Example 339

SMILES CCCS(=O)(=O)Nc1cc(nc(Oc2c(F)cccc2CC)n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=BGIRRJVWWVBJRK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345794   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM345794(US10202360, Example 339 | N-(2-(2-ethyl-6-fluoroph...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent