BDBM345809 N-(6-(1-methyl-6-oxo-1,6- dihydropyridin-3-yl)-2-((tetrahydro- 2H-pyran-4-yl)oxy)pyrimidin-4- yl)propane-1-sulfonamide::US10202360, Example 354

SMILES CCCS(=O)(=O)Nc1cc(nc(OC2CCOCC2)n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=YLCWSCRQMRSOAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345809   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM345809(US10202360, Example 354 | N-(6-(1-methyl-6-oxo-1,6...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent