BDBM345815 5-(3,6-dichloro-10,10-dioxido-2,4-dioxa-10-thia-11-aza-1(2,4)-pyrimidina-3(1,3)-benzenacycloundecaphan-6-en-16-yl)-1-methylpyridin-2(1H)-one::US10202360, Example 360

SMILES Cn1cc(ccc1=O)-c1cc2NS(=O)(=O)CC\C=C/COc3cc(Cl)cc(Oc(n2)n1)c3Cl

InChI Key InChIKey=RWDYCTJSDGLAFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345815   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM345815(US10202360, Example 360 | 5-(3,6-dichloro-10,10-di...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent