BDBM346308 US10202377, Compound 234

SMILES CN1CCN(CC1)c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cncnc1

InChI Key InChIKey=INJYVLYMLHZNAA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346308   

TargetTGF-beta receptor type-1(Human)
Samumed

US Patent
LigandPNGBDBM346308(US10202377, Compound 234)
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetProto-oncogene Wnt-1(Human)
Samumed

US Patent
LigandPNGBDBM346308(US10202377, Compound 234)
Affinity DataIC50: 798nMAssay Description:The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent