BDBM347139 2-(4-((2-ethoxy-5-(4-methylpiperazin-1-yl) phenyl)(methyl)amino)phenoxy) pyrido[3,4-d]pyrimidin-4-ol::US10202381, Example 146

SMILES CCOc1ccc(cc1N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1C)N1CCN(C)CC1

InChI Key InChIKey=AJAWOCBVVWSTSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347139   

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM347139(2-(4-((2-ethoxy-5-(4-methylpiperazin-1-yl) phenyl)...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent