BDBM347429 US10869871, ID # SW209415::US20230285402, ID # SW209415-(+)-isomer::US20240043440, Example SW209415::US9789116, SW209415

SMILES CCCCS(=O)c1sc2nc(cc(-c3cnc(C)n3C)c2c1N)-c1nccs1

InChI Key InChIKey=LKPKDKDBZLBUIC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 347429   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347429(US9789116, SW209415 | US10869871, ID # SW209415 | ...)
Affinity DataIC50: 1.30nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347429(US9789116, SW209415 | US10869871, ID # SW209415 | ...)
Affinity DataIC50: 1.30nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347429(US9789116, SW209415 | US10869871, ID # SW209415 | ...)
Affinity DataIC50: 2.10nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (5 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347429(US9789116, SW209415 | US10869871, ID # SW209415 | ...)
Affinity DataIC50: 2.60nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent