BDBM347525 3-Chloro-5-{[3-(2-methoxyphenyl)piperidin-1-yl]carbonyl}pyridazine::US9790201, 11::US9790201, 49::US9790201, 50::US9790201, 51

SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(C)cc1

InChI Key InChIKey=SYIMSJKOLQJRNV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 347525   

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM347525(US9790201, 49 | 3-Chloro-5-{[3-(2-methoxyphenyl)pi...)
Affinity DataIC50: 290nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM347525(US9790201, 49 | 3-Chloro-5-{[3-(2-methoxyphenyl)pi...)
Affinity DataIC50: 310nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM347525(US9790201, 49 | 3-Chloro-5-{[3-(2-methoxyphenyl)pi...)
Affinity DataIC50: 420nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM347525(US9790201, 49 | 3-Chloro-5-{[3-(2-methoxyphenyl)pi...)
Affinity DataIC50: 990nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent