BDBM347654 2-methyl-6-[2-[4-[2-methyl-4-(4-pyridyl)pyrazol-3-yl]phenyl]ethynyl]pyridine::US9790203, Example 26

SMILES Cc1cccc(n1)C#Cc1ccc(cc1)-c1c(cnn1C)-c1ccncc1

InChI Key InChIKey=XXCQAXXQJAEKBI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347654   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Abbvie

US Patent

LigandBDBM347654(2-methyl-6-[2-[4-[2-methyl-4-(4-pyridyl)pyrazol-3-...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/9/2019
Entry Details
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