BDBM347658 2-[2-[4-[4-(4-methoxyphenyl)-1-methyl-pyrazol-3-yl]phenyl]ethynyl]-6-methylpyridine::US9790203, Example 31

SMILES COc1ccc(cc1)-c1cn(C)nc1-c1ccc(cc1)C#Cc1cccc(C)n1

InChI Key InChIKey=QQMZXFJWIGZOCF-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347658   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Abbvie

US Patent

LigandBDBM347658(2-[2-[4-[4-(4-methoxyphenyl)-1-methyl-pyrazol-3-yl...)Copy SMILESCopy InChI

Affinity DataIC50: 150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/9/2019
Entry Details
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