BDBM347665 1-(4-((2-((3-(2-(Dimethylamino)ethoxy)phenyl)amino)pyrimidin-4-yl)oxy)naphthalen-1-yl)-3-(3-(2-methylbut-3-yn-2-yl)-1-(p-tolyl)-1H-pyrazol-5-yl)urea::US9790209, Example 6

SMILES CN(C)CCOc1cccc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)C(C)(C)C#C)c4ccccc34)n2)c1

InChI Key InChIKey=QGLFOZKCZAPXOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347665   

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandPNGBDBM347665(1-(4-((2-((3-(2-(Dimethylamino)ethoxy)phenyl)amino...)
Affinity DataIC50: 243nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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Date in BDB:
9/9/2019
Entry Details
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