BDBM347668 1-(2,3-Dichloro-4-((2-((7-methyl-1H-indazol-5-yl)amino)pyrimidin-4-yl)oxy)phenyl)-3-(3-(2-methylbut-3-yn-2-yl)-1-(p-tolyl)-1H-pyrazol-5-yl)urea::US9790209, Example 9

SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cc(C)c4[nH]ncc4c3)n2)c(Cl)c1Cl)C(C)(C)C#C

InChI Key InChIKey=LCMJCICVZJWUKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347668   

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandPNGBDBM347668(1-(2,3-Dichloro-4-((2-((7-methyl-1H-indazol-5-yl)a...)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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Date in BDB:
9/9/2019
Entry Details
US Patent