BDBM347691 (E)-2-(4-Chlorophenoxy)-3- (dimethylamino)-1-[4- (trifluoromethyl)phenyl]prop-2-en-1-one::US9790217, 14

SMILES CN(C)\C=C(\Oc1ccc(Cl)cc1)C(=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=ZLGSPZIJIGOYHK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347691   

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM347691((E)-2-(4-Chlorophenoxy)-3- (dimethylamino)-1-[4- (...)
Affinity DataEC50:  2.03nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM347691((E)-2-(4-Chlorophenoxy)-3- (dimethylamino)-1-[4- (...)
Affinity DataEC50:  2.67nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent