BDBM347694 (E)-1-(2-Chloro-4-methylsulfanyl- phenyl)-2-(4-chlorophenoxy)-3- (dimethylamino)prop-2-en-1-one::US9790217, 17

SMILES CSc1ccc(C(=O)C(\Oc2ccc(Cl)cc2)=C/N(C)C)c(Cl)c1

InChI Key InChIKey=WVCHAWQSSDDNNE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347694   

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM347694((E)-1-(2-Chloro-4-methylsulfanyl- phenyl)-2-(4-chl...)
Affinity DataEC50:  0.0610nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM347694((E)-1-(2-Chloro-4-methylsulfanyl- phenyl)-2-(4-chl...)
Affinity DataEC50:  0.522nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent