BDBM348346 US10577374, Compound 69::US9790229, Compound 69

SMILES O=c1c(Nc2ccccc2)c(Nc2cccc(c2)C2CCCN(C2)c2ncnc3[nH]ccc23)c1=O

InChI Key InChIKey=UEILWJONWOUHOG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 348346   

TargetTyrosine-protein kinase BTK(Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348346(US9790229, Compound 69 | US10577374, Compound 69)
Affinity DataIC50: 1.00E+4nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348346(US9790229, Compound 69 | US10577374, Compound 69)
Affinity DataIC50: 1.00E+4nMAssay Description:BTK-POLYGAT-LS ASSAY. The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348346(US9790229, Compound 69 | US10577374, Compound 69)
Affinity DataIC50: 4.40E+4nMAssay Description:Reversible inhibition of recombinant full-length N-terminal 6-His-tagged human BTK expressed in baculovirus infected Sf21 insect cells using fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed