BDBM349228 (4R)-6-[1-(2-hydroxyethyl)-3-(1-methylpyrazol-4-yl)indazol-5-yl]-4-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one::US10206931, Example 35

SMILES CN\C=C(/C=N)C(=N)c1cc(ccc1NCCO)-c1cccc2NC(=O)C[C@@H](C)Nc12

InChI Key InChIKey=SAMHRXKRKNWIPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 349228   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM349228((4R)-6-[1-(2-hydroxyethyl)-3-(1-methylpyrazol-4-yl...)
Affinity DataIC50: 57nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent