BDBM350126 5-(2-(2,4-dimethylphenyl)- 2-oxoethyl)-1-(S,S-dioxo- tetrahydrothiophen-3-yl)- 1H-pyrazolo[3,4- d]pyrimidin-4(5H)-one::US10208043, # 28::US10941146, # 28

SMILES Cc1ccc(C(=O)Cn2cnc3n(ncc3c2=O)C2CCS(=O)(=O)C2)c(C)c1

InChI Key InChIKey=KYJFYLKBWMNNEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350126   

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350126(US10208043, # 28 | 5-(2-(2,4-dimethylphenyl)- 2-ox...)
Affinity DataIC50: 4.70E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350126(US10208043, # 28 | 5-(2-(2,4-dimethylphenyl)- 2-ox...)
Affinity DataIC50: 4.70E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent