BDBM350312 8-(2-hydroxy-1-(tetrazolo[1,5-a]quinolin-7-yl)ethyl)-2-(4-methyl-5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one::US10208064, Example 28

SMILES CC1=C(COC1=O)N1CCC2(CCN(CC2)C(CO)c2ccc3c(ccc4nnnn34)c2)C1=O

InChI Key InChIKey=YHZGAPICAKWCIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350312   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandPNGBDBM350312(8-(2-hydroxy-1-(tetrazolo[1,5-a]quinolin-7-yl)ethy...)
Affinity DataIC50: 18nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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