BDBM35081 N-acylpolyamine (NAPA) scaffold, 28

SMILES CC(C)CCC(=O)NC(CCC(O)=O)CN(C(CCCCN)CN(C(CCC(O)=O)CN(CCC(N)=O)C(=O)NCCCCc1ccc(F)cc1)C(=O)NCCc1ccc(C)cc1)C(=O)NCCCC1CCCCC1

InChI Key InChIKey=CCIFGPJUSMTRPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35081   

LigandPNGBDBM35081(N-acylpolyamine (NAPA) scaffold, 28)
Affinity DataIC50: 1.30E+4nMpH: 7.6 T: 2°CAssay Description:Inhibitory activities of NAPAs were measured by fluorescence anisotropy competition experiments. Protein was incubated with fluorescein-labeled huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Nih

LigandPNGBDBM35081(N-acylpolyamine (NAPA) scaffold, 28)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activities of NAPAs were measured by fluorescence anisotropy competition experiments. Protein was incubated with fluorescein-labeled huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed