BDBM351276 (−)-6-[4-[(1S)-1-(1-Acetylpiperidin-4-yl)ethyl]-1H-pyrazol-3-yl]-5-fluoro-1-methyl-3,4-dihydroquinolin-2-one::US9796702, 37

SMILES C[C@@H](C1CCN(CC1)C(C)=O)c1c[nH]nc1-c1ccc2N(C)C(=O)CCc2c1F

InChI Key InChIKey=HUVLJWOWKSCYTO-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 351276   

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM351276(US9796702, 37 | (−)-6-[4-[(1S)-1-(1-Acetylpi...)
Affinity DataEC50:  0.0640nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM351276(US9796702, 37 | (−)-6-[4-[(1S)-1-(1-Acetylpi...)
Affinity DataEC50:  4.58nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent