BDBM351497 N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(3- piperazin-1-yl-1,2,4-oxadiazol-5- yl)methyl]oxy}quinazolin-4-amine::US9796704, Entry 217

SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(no1)N1CCCC1

InChI Key InChIKey=MLXXNWHIZCXWDE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 351497   

TargetEpidermal growth factor receptor(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351497(US9796704, Entry 217 | N-(3,4-dichlorophenyl)-6-(m...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351497(US9796704, Entry 217 | N-(3,4-dichlorophenyl)-6-(m...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEphrin type-A receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351497(US9796704, Entry 217 | N-(3,4-dichlorophenyl)-6-(m...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEphrin type-B receptor 4(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351497(US9796704, Entry 217 | N-(3,4-dichlorophenyl)-6-(m...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351497(US9796704, Entry 217 | N-(3,4-dichlorophenyl)-6-(m...)
Affinity DataIC50: 525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent