BDBM351500 N-(3,4-dichlorophenyl)-7-({[3-(4- ethylpiperazin-1-yl)-1,2,4-oxadiazol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine::US9796704, Entry 220

SMILES CCN1CCN(CC1)c1noc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)n1

InChI Key InChIKey=FGHXOSBHGQKMBX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 351500   

TargetEpidermal growth factor receptor(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351500(US9796704, Entry 220 | N-(3,4-dichlorophenyl)-7-({...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEphrin type-B receptor 4(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351500(US9796704, Entry 220 | N-(3,4-dichlorophenyl)-7-({...)
Affinity DataIC50: 525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEphrin type-A receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351500(US9796704, Entry 220 | N-(3,4-dichlorophenyl)-7-({...)
Affinity DataIC50: 525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351500(US9796704, Entry 220 | N-(3,4-dichlorophenyl)-7-({...)
Affinity DataIC50: 525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351500(US9796704, Entry 220 | N-(3,4-dichlorophenyl)-7-({...)
Affinity DataIC50: 525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent