BDBM351942 Preparation of 5-(2-((1R,5S)-3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-4-((2-methoxyethyl)amino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenylmethanol ::US9796732, Compound 12

SMILES COCCN(C)c1nc(nc2nc(ccc12)-c1ccc(OC)c(CO)c1)N1C2CCC1COC2

InChI Key InChIKey=CTXKXVRHNXMJQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351942   

TargetSerine/threonine-protein kinase mTOR(Human)
Shandong Luoxin Pharmaceutical Group Stock

US Patent
LigandPNGBDBM351942(Preparation of 5-(2-((1R,5S)-3-oxa-8-azabicyclo[3....)
Affinity DataIC50: 57nMAssay Description:The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent