BDBM351943 Preparation of (5-(2,4-dimorpholinylpyrido[4,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol ::US9796732, Compound 13

SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3CCOCC3)c2cn1)N1CCOCC1

InChI Key InChIKey=OLSIXTBNDRWVEV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351943   

TargetSerine/threonine-protein kinase mTOR(Human)
Shandong Luoxin Pharmaceutical Group Stock

US Patent
LigandPNGBDBM351943(Preparation of (5-(2,4-dimorpholinylpyrido[4,3-d]p...)
Affinity DataIC50: 451nMAssay Description:The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent