BDBM351961 Preparation of 3-(4-morpholinyl-7-phenylpyrido[4,3-d]pyrimidin-2-yl)-8-oxa-3-azabicyclo[3.2.1]octane ::US9796732, Compound 28

SMILES C1CC2CN(CC1O2)c1nc(N2CCOCC2)c2cnc(cc2n1)-c1ccccc1

InChI Key InChIKey=NNGOGPWHTVGWGT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351961   

TargetSerine/threonine-protein kinase mTOR(Human)
Shandong Luoxin Pharmaceutical Group Stock

US Patent
LigandPNGBDBM351961(Preparation of 3-(4-morpholinyl-7-phenylpyrido[4,3...)
Affinity DataIC50: 435nMAssay Description:The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent