BDBM351970 Preparation of (3S,3′S)-4,4′-(7-phenyl pyrimido[4,5-d]pyrimidin-2,4-diyl)-di(3-methyl morpholine) ::US9796732, Compound 33

SMILES C[C@H]1COCCN1c1nc(N2CCOC[C@@H]2C)c2cnc(nc2n1)-c1ccccc1

InChI Key InChIKey=VVQXLUWYLDAEJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351970   

TargetSerine/threonine-protein kinase mTOR(Human)
Shandong Luoxin Pharmaceutical Group Stock

US Patent
LigandPNGBDBM351970(Preparation of (3S,3′S)-4,4′-(7-phenyl...)
Affinity DataIC50: 413nMAssay Description:The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent