BDBM351971 Preparation of 3,3′-(7-phenylpyrimido[4,5-d]pyrimidin-2,4-diyl)-di(8-oxa-3-azabicyclo[3.2.1]octane) ::US9796732, Compound 34

SMILES C1CC2CN(CC1O2)c1nc(N2CC3CCC(C2)O3)c2cnc(nc2n1)-c1ccccc1

InChI Key InChIKey=WMOMDLULDCLWSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351971   

TargetSerine/threonine-protein kinase mTOR(Human)
Shandong Luoxin Pharmaceutical Group Stock

US Patent
LigandPNGBDBM351971(Preparation of 3,3′-(7-phenylpyrimido[4,5-d]...)
Affinity DataIC50: 195nMAssay Description:The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent