BDBM351972 Preparation of 3-(2,4-di(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)pyrido[2,3-d]pyrimidin-7-yl)-N-methylbenzamide ::US9796732, Compound 35

SMILES CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1C2CCC1COC2)N1C2CCC1COC2

InChI Key InChIKey=STNZYTKNOWJAPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351972   

TargetSerine/threonine-protein kinase mTOR(Human)
Shandong Luoxin Pharmaceutical Group Stock

US Patent
LigandPNGBDBM351972(Preparation of 3-(2,4-di(3-oxa-8-azabicyclo[3.2.1]...)
Affinity DataIC50: 60nMAssay Description:The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent