BDBM35198 pyrimidoindolone, 11g

SMILES COc1ccc(OC[C@@H]2CCCN2S(=O)(=O)c2ccc3N4CC(C)(C)CN=C4C(=O)c3c2)c(Cl)c1

InChI Key InChIKey=YRLZYPOZONFYBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35198   

TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35198(pyrimidoindolone, 11g)
Affinity DataIC50: 82nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed