BDBM352091 (2S,4R)-1-(2-(3-acetyl- 5-(1-acetyl-1,2,3,6- tetrahydropyridin-4-yl)- 1H-indol-1-yl)acetyl)- N-(2'-chloro-2- fluorobiphenyl-3-yl)-4- fluoropyrrolidine-2- carboxamide::US9796741, cmp No. 28

SMILES CC(=O)N1CCC(=CC1)c1ccc2n(CC(=O)N3C[C@H](F)C[C@H]3C(=O)Nc3cccc(c3F)-c3ccccc3Cl)cc(C(N)=O)c2c1

InChI Key InChIKey=HFQGIBMSQGCGQJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352091   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM352091((2S,4R)-1-(2-(3-acetyl- 5-(1-acetyl-1,2,3,6- tetra...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent