BDBM35217 pyrimidoindolone, 22f

SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc2N3CC(C)(C)CN=C3C(=O)c2c1

InChI Key InChIKey=NOTJVLIMAAPVJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35217   

TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35217(pyrimidoindolone, 22f)
Affinity DataIC50: 1.50E+3nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed