BDBM35243 3-(phenylsulfonyl)-1H-indole, 18e

SMILES CCCNCCc1cccc2[nH]cc(c12)S(=O)(=O)c1ccccc1

InChI Key InChIKey=CQNQTEGBNDNNMO-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35243   

Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandPNGBDBM35243(3-(phenylsulfonyl)-1H-indole, 18e)
Affinity DataKi:  367nM IC50: 1.08E+3nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
LigandPNGBDBM35243(3-(phenylsulfonyl)-1H-indole, 18e)
Affinity DataKi:  487nM ΔG°:  -8.95kcal/mole IC50: 302nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed