BDBM353032 4-Methylphenyl 5-{4-[(4-hydroxyphenyl)(methyl)carbamoyl]-1,5-dimethyl-1H-pyrrol-2-yl}-6-[(3R)-3-methyl-1,2,3,4-tetrahydroisoquinoline-2-carbonyl]-2,3-dihydro-1H-isoindole-2-carboxylate::US9809574, Example 107

SMILES C[C@@H]1Cc2ccccc2CN1C(=O)c1cc2CN(Cc2cc1-c1cc(C(=O)N(C)c2ccc(O)cc2)c(C)n1C)C(=O)Oc1ccc(C)cc1

InChI Key InChIKey=ZYRKPAHYTNPFFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 353032   

TargetApoptosis regulator Bcl-2(Human)
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US Patent
LigandPNGBDBM353032(US9809574, Example 107 | 4-Methylphenyl 5-{4-[(4-h...)
Affinity DataIC50: 3.5nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
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Date in BDB:
10/7/2019
Entry Details
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