BDBM3536 4-N-(3-bromophenyl)-6-N,6-N-dimethylquinazoline-4,6-diamine::CHEMBL52015::PD153035 Analog 36

SMILES CN(C)c1ccc2ncnc(Nc3cccc(Br)c3)c2c1

InChI Key InChIKey=BNMOXMJDRLQWOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3536   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3536(4-N-(3-bromophenyl)-6-N,6-N-dimethylquinazoline-4,...)
Affinity DataIC50: 84nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3536(4-N-(3-bromophenyl)-6-N,6-N-dimethylquinazoline-4,...)
Affinity DataIC50: 85nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed