BDBM35402 MLS000093276::N-[2-(4-morpholinyl)-5-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine::N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine::N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-a]quinoxalin-4-amine::SMR000028898::[2-morpholino-5-(trifluoromethyl)phenyl]-([1,2,4]triazolo[4,3-a]quinoxalin-4-yl)amine::cid_3242631

SMILES FC(F)(F)c1ccc(N2CCOCC2)c(Nc2nc3ccccc3n3cnnc23)c1

InChI Key InChIKey=XJFJINZMGHGLPK-UHFFFAOYSA-N

Data  8 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 35402   

TargetG-protein coupled receptor 55(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM35402(N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-[1,...)
Affinity DataEC50:  4.18E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35402(N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-[1,...)
Affinity DataIC50: 2.27E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 6(Rat)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35402(N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-[1,...)
Affinity DataIC50: 5.00E+4nMAssay Description:The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35402(N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-[1,...)
Affinity DataIC50: 5.00E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 6(Rat)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35402(N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-[1,...)
Affinity DataIC50: 5.00E+4nMAssay Description:The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35402(N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-[1,...)
Affinity DataIC50: 5.00E+4nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 6(Rat)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35402(N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-[1,...)
Affinity DataIC50: 5.00E+4nMAssay Description:The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35402(N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-[1,...)
Affinity DataIC50: 5.00E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetLysosomal acid glucosylceramidase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM35402(N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-[1,...)
Affinity DataEC50: >5.00E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetM-phase inducer phosphatase 2(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35402(N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-[1,...)
Affinity DataIC50: 5.00E+4nMAssay Description:The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay