BDBM3542 4-N-(3-bromophenyl)-7-N,7-N-dimethylquinazoline-4,7-diamine::CHEMBL90013::PD153035 Analog 42

SMILES CN(C)c1ccc2c(Nc3cccc(Br)c3)ncnc2c1

InChI Key InChIKey=OGYJJQMXMIANLJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3542   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3542(4-N-(3-bromophenyl)-7-N,7-N-dimethylquinazoline-4,...)
Affinity DataIC50: 11nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3542(4-N-(3-bromophenyl)-7-N,7-N-dimethylquinazoline-4,...)
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed