BDBM354755 US9814704, Example 32

SMILES Cc1ccc(cc1)S(=O)(=O)n1cc(-c2ccc3[nH]ccc3c2)c2cc(cnc12)-c1ccc(C=O)cc1

InChI Key InChIKey=ANQUZKPKKVNPTD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354755   

TargetMitogen-activated protein kinase kinase kinase 11(Human)
The University of Rochester

US Patent
LigandPNGBDBM354755(US9814704, Example 32)
Affinity DataIC50: 100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
US Patent