BDBM355552 N-{(1S)-1-[2-chloro-4- (trifluoromethyl)phenyl]-2-hydroxy- 1-methylethyl}-6-oxo-2-phenyl-1,6- dihydropyrimidine-4-carboxamide::US9815796, Example 643

SMILES C[C@](CO)(NC(=O)c1cc(=O)[nH]c(n1)-c1ccccc1)c1ccc(cc1Cl)C(F)(F)F

InChI Key InChIKey=XYSWGFYTDYAMJG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355552   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM355552(US9815796, Example 643 | N-{(1S)-1-[2-chloro-4- (t...)
Affinity DataKi:  0.5nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
10/13/2019
Entry Details
US Patent