BDBM355645 (2S,3S,4S)-1-[2-(3-Acetyl-indazol-1- yl)-acetyl]-4-fluoro-3-methoxy- pyrrolidine-2-carboxylic acid ((1R,2S)-2-phenyl-cyclopropyl)- amide::US9815819, 10

SMILES CO[C@@H]1[C@@H](F)CN([C@@H]1C(=O)N[C@@H]1C[C@H]1c1ccccc1)C(=O)Cn1nc(C(C)=O)c2ccccc12

InChI Key InChIKey=QPVHNTLUUHCFCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355645   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM355645(US9815819, 10 | (2S,3S,4S)-1-[2-(3-Acetyl-indazol-...)
Affinity DataIC50: 40nMAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
US Patent