BDBM355650 5-Methyl-1-{2-oxo-2-[(1R,3S,5R)-3- ((1R,2S)-2-phenyl- cyclopropylcarbamoyl)-2-aza- bicyclo[3.1.0]hex-2-yl]-ethyl}-1H- pyrazolo[3,4-]pyridine-3-carboxylic acid amide::US9815819, 15

SMILES Cc1cc2c(nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)N[C@@H]3C[C@H]3c3ccccc3)c2cn1)C(N)=O

InChI Key InChIKey=DHTZZSXUNMIQHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355650   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM355650(US9815819, 15 | 5-Methyl-1-{2-oxo-2-[(1R,3S,5R)-3-...)
Affinity DataIC50: 115nMAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
US Patent