BDBM355653 1-{2-[(2S,4R)-4-Fluoro-2-((1R,2S)- 2-phenyl-cyclopropylcarbamoyl)- pyrrolidin-1-yl]-2-oxo-ethyl}-1H- indazole-3-carboxylic acid amide::US9815819, 18

SMILES NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)N[C@@H]2C[C@H]2c2ccccc2)c2ccccc12

InChI Key InChIKey=NMJRIUGLMDYYJW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355653   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM355653(US9815819, 18 | 1-{2-[(2S,4R)-4-Fluoro-2-((1R,2S)-...)
Affinity DataIC50: 44nMAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
US Patent