BDBM35570 1H-benzo[de]isoquinoline-1,3(2H)-dione, 19

SMILES Brc1cccc(c1)N1C(=O)c2cccc3c(NC4CCN(Cc5ccccc5)CC4)ccc(C1=O)c23

InChI Key InChIKey=KGQNAINAEOIJHF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35570   

TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35570(1H-benzo[de]isoquinoline-1,3(2H)-dione, 19)
Affinity DataIC50: 14nM EC50:  2.20E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35570(1H-benzo[de]isoquinoline-1,3(2H)-dione, 19)
Affinity DataIC50: 43nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed