BDBM35571 1H-benzo[de]isoquinoline-1,3(2H)-dione, 20::cis-isomers

SMILES OC(=O)[C@@H]1CC[C@@H](CC1)Nc1ccc2C(=O)N(C(=O)c3cccc1c23)c1cccc(Br)c1

InChI Key InChIKey=AYCKJOQAUPGGNB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35571   

TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35571(cis-isomers | 1H-benzo[de]isoquinoline-1,3(2H)-dio...)
Affinity DataIC50: 42nM EC50:  3.80E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35571(cis-isomers | 1H-benzo[de]isoquinoline-1,3(2H)-dio...)
Affinity DataIC50: 110nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed