BDBM355744 US9815832, 21::[3-(4-Chloro-3-fluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl](3-fluoroazetidin-1-yl)methanone

SMILES FC1CN(C1)C(=O)c1nc2cccnc2n1-c1ccc(Cl)c(F)c1

InChI Key InChIKey=FLCQAEUNWDIZPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355744   

LigandPNGBDBM355744(US9815832, 21 | [3-(4-Chloro-3-fluorophenyl)-3H-im...)
Affinity DataIC50: 42.6nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
US Patent

LigandPNGBDBM355744(US9815832, 21 | [3-(4-Chloro-3-fluorophenyl)-3H-im...)
Affinity DataIC50: 316nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
US Patent