BDBM355750 N-Cyclopropyl-3-(3,4-dichlorophenyl)-3H-imidazo[4,5-b]pyridine-2-carboxamide::US9815832, 27

SMILES Clc1ccc(cc1Cl)-n1c(nc2cccnc12)C(=O)NC1CC1

InChI Key InChIKey=LZTJYRYBQLTRFF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 355750   

LigandPNGBDBM355750(US9815832, 27 | N-Cyclopropyl-3-(3,4-dichloropheny...)
Affinity DataIC50: 12.2nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
US Patent

LigandPNGBDBM355750(US9815832, 27 | N-Cyclopropyl-3-(3,4-dichloropheny...)
Affinity DataIC50: 511nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
US Patent

LigandPNGBDBM355750(US9815832, 27 | N-Cyclopropyl-3-(3,4-dichloropheny...)
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed