BDBM355756 3-(3-Chloro-4-methylphenyl)-N-cyclopropyl-3H-imidazo[4,5-b]pyridine-2-carboxamide::US9815832, 33

SMILES Cc1ccc(cc1Cl)-n1c(nc2cccnc12)C(=O)NC1CC1

InChI Key InChIKey=WMHAFHPEFGQMEO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 355756   

LigandPNGBDBM355756(US9815832, 33 | 3-(3-Chloro-4-methylphenyl)-N-cycl...)
Affinity DataIC50: 15.9nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
US Patent

LigandPNGBDBM355756(US9815832, 33 | 3-(3-Chloro-4-methylphenyl)-N-cycl...)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
LigandPNGBDBM355756(US9815832, 33 | 3-(3-Chloro-4-methylphenyl)-N-cycl...)
Affinity DataIC50: 1.23E+3nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
US Patent

LigandPNGBDBM355756(US9815832, 33 | 3-(3-Chloro-4-methylphenyl)-N-cycl...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D3 expressed in baculovirus infected Sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed