BDBM356102 US9815846, Compound 102

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2ccc(CC(N)=O)nc2-c2ccccc2)c(F)cc1C(F)(F)F

InChI Key InChIKey=VKGWMKNXEWYJKG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356102   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356102(US9815846, Compound 102)
Affinity DataIC50: 0.790nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details
US Patent