BDBM356220 2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(2-((2- oxopiperidin-1-yl)methyl)-4- phenylpyrimidin-5-yl)-4- (trifluoromethyl)benzamide::US9815846, Compound 220

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cnc(CN3CCCCC3=O)nc2-c2ccccc2)c(F)cc1C(F)(F)F

InChI Key InChIKey=WSEWGTPRJVCSCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356220   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356220(US9815846, Compound 220 | 2-fluoro-5-(1-methyl-1H-...)
Affinity DataIC50: 1nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details
US Patent