BDBM356574 N-(2-Hydroxypropyl)-2-(4-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}-1H-pyrazol-1-yl)propanamide::US10213427, Example 63

SMILES CC(O)CNC(=O)C(C)N\C=C(/C=N)c1cnn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1

InChI Key InChIKey=CUFRYDKFIMRNTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356574   

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM356574(N-(2-Hydroxypropyl)-2-(4-{3-[3-({[(2,2,2-trifluoro...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to ...More data for this Ligand-Target Pair
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Date in BDB:
10/20/2019
Entry Details
US Patent