BDBM356673 N-(4′-((trans)-2-((4-aminocyclohexyl)amino)cyclopropyl)-6-methoxy-[1,1′-biphenyl]-3-yl)methanesulfonamide::US10214477, Example 48

SMILES COc1ccc(NS(C)(=O)=O)cc1-c1ccc(cc1)C1CC1N[C@H]1CC[C@H](N)CC1

InChI Key InChIKey=IJWYHMIMXOCAJF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 356673   

TargetAmine oxidase [flavin-containing] A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM356673(N-(4′-((trans)-2-((4-aminocyclohexyl)amino)c...)
Affinity DataIC50: 1.75E+4nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM356673(N-(4′-((trans)-2-((4-aminocyclohexyl)amino)c...)
Affinity DataIC50: 1.00E+5nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM356673(N-(4′-((trans)-2-((4-aminocyclohexyl)amino)c...)
Affinity DataIC50: 27nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent