BDBM356677 US10214477, Example 52

SMILES NC1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(cc1)-c1cccc(NS(=O)(=O)N2CCNCC2)c1

InChI Key InChIKey=GVFVFSPQLVQDNV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 356677   

TargetAmine oxidase [flavin-containing] A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM356677(US10214477, Example 52)
Affinity DataIC50: 8.78E+6nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM356677(US10214477, Example 52)
Affinity DataIC50: 6.50E+4nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM356677(US10214477, Example 52)
Affinity DataIC50: 19nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent